Papers | Ville Langén

Featured Publications

Trends in Positive Life Orientation Among 70-Year-Olds: A Comparison of Two Finnish Cohorts Born 20 Years Apart

Trends in Positive Life Orientation Among 70-Year-Olds: A Comparison of Two Finnish Cohorts Born 20 Years Apart

We explored the increase in positive life orientation among older individuals in a Nordic setting, comparing cohorts born in 1920 and 1940, to identify trends and gender disparities. Our research revealed that the later cohort reported a higher sense of being needed, more future plans, and less loneliness, indicating a substantial improvement in their overall well-being, despite ongoing gender differences. These findings suggest a significant enhancement in the quality of life for the elderly over recent decades, emphasizing the need for tailored societal and healthcare policies to support this positive trend.

Feb 1, 2024

Publications in International Peer-Reviewed Journals

N. Kiuru, S. Reinilä, Ville Langén, J. Jaakkola, K. E. J. Airaksinen, O. Halminen, J. Putaala, P. Mustonen, J. Haukka, J. Hartikainen, A. Luojus, M. Niemi, M. Linna, M. Lehto, G. Y. H. Lip, K. Teppo (2026). Trends in Polypharmacy Among Patients With Atrial Fibrillation: A Report From the Finnish AntiCoagulation in Atrial Fibrillation Nationwide Cohort Study. J Am Heart Assoc.

Ville Langén, A. Winstén, K. Teppo, T. Pohjonen, J. Laukkanen, FinnGen, A. Mannermaa, T. J. Niiranen, J. Palmu (2026). Machine Learning-Based Prediction of Drug-Induced QTc Changes in a Large Finnish Biobank Cohort. Clin Transl Sci (submitted).

A. K. Winstén, Ville Langén, K. E. J. Airaksinen, K. Teppo (2025). Estimating the Stroke Risk Threshold for Initiating Non-Vitamin K Antagonist Oral Anticoagulation in Atrial Fibrillation: Markov Decision Model Analysis. Circ Cardiovasc Qual Outcomes.

H. Diab, Ville Langén, L. F. Yeo, V. Salomaa, A. Havulinna, L. Lahti, K. Pärnänen, R. Knight, S. Jalkanen, M. Salmi, T. Niiranen, J. Palmu (2025). Associations between gut microbiome and circulating cytokines: a cross-sectional analysis in the FINRISK 2002 population cohort. Gut Pathog.

E. Jalli, J. Jaakkola, Ville Langén, K. E. J. Airaksinen, O. Halminen, J. Putaala, P. Mustonen, J. Haukka, J. Hartikainen, M. Linna, E. Kouki, M. Lehto, K. Teppo (2025). Venous thromboembolisms and stroke risk in patients with atrial fibrillation: a nationwide cohort study. Europace.

Peer-reviewed Finnish publications

Salla Ranta, Ville Langén, Maria Nuotio, Laura Ekblad (2023). EKG-löydökset vaikeuttavat muistisairauden lääkehoitoa. Suom Lääkäril.

Reetta Laiho, Maija Valta, Antti Järvi, Jarmo Oksi, Ville Langén (2023). Mystinen leukasärky, kaksoiskuvat ja hajoavat punasolut. Suom Lääkäril.

Ville Langén, Jari Laukkanen, Teemu Niiranen (2021). Nostaako krooninen tulehdus verenpainetta?. Duodecim.

Other Published Works

Ville Langén (2018). Thesis: Thyroid-stimulating hormone : reference range and relation to cardiovascular risk.

Ville Langén, Teemu Niiranen (2016). HDL-hypoteesi valtimotautien tutkimuksessa ja hoidossa – pettymysten jälkeen edessä renessanssi?. Sydänääni.